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 上海勁馬生物提供完善的Rat Activin-A Protein/重組大鼠激活素-A（Activin-A）蛋白的基本參數(shù)，如有任何產(chǎn)品問題咨詢。您的滿意是我們zui大的動(dòng)力。

背景資料 激活素（Activin）屬于轉(zhuǎn)化生長因子超家族.是1986年從豬卵泡液中獲得，具有刺激垂體前葉腺細(xì)胞（FSH）分泌作用雙鏈糖蛋白.激活素（Activin）在初期胚胎形成、血管平滑肌增殖、動(dòng)脈硬化、神經(jīng)分化誘導(dǎo)、造血細(xì)胞增殖分化、內(nèi)分泌中樞垂體性激素分泌調(diào)節(jié)等諸多方面發(fā)揮作用.是近幾年來關(guān)注比較多多功能細(xì)胞因子.
產(chǎn)品描述 Active form Activin-A Rat Recombinant produced in e.coli is a homodimeric， non-glycosylated， polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2kDa. The Active form Activin-A is purified by standard chromatographic techniques.
來源宿主 大腸桿菌中重組表達(dá)
序列

MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVI

NHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS.

溶解建議 提供的重組大鼠激活素-A產(chǎn)品形式為凍干粉末.推薦加無菌的蒸餾的無熱源的水以配制工作儲存液到不低于100ug/ml，后繼實(shí)驗(yàn)過程中可根據(jù)實(shí)驗(yàn)要求進(jìn)一步稀釋.
保存建議 大鼠激活素-A產(chǎn)品在室溫條件下可以保存3周，應(yīng)該置于-18℃或更低溫度下干燥保存.重新溶解后可置于4℃保存2-7天，為長期使用，保存溫度應(yīng)低于-18℃.請避免反復(fù)凍融.

名稱 Rat Activin-A Protein/重組大鼠激活素-A（Activin-A）蛋白
中文名 Rat Activin-A Protein/重組大鼠激活素-A（Activin-A）蛋白
基本描述 Activins are homodimers or heterodimers of the different β subunit isoforms, part of the TGFβ family. Mature Activin A has two 116 amino acids residues βA subunits (βA-βA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.
分子別稱 Inhba, Inhibin beta A, FSH releasing protein
分子種屬 Mouse
表達(dá)標(biāo)簽 His，S
表達(dá)宿主 E. coli
純度 > 95 % as determined by SDS-PAGE
緩沖液 Lyophilized from sterile PBS, pH 7.4
保存方法 -70°C，應(yīng)避免反復(fù)凍融。
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